Diabetes is a leading cause of kidney damage worldwide. One of its most serious complications is Diabetic Nephropathy—a condition where high blood sugar levels gradually harm the kidneys' filtering units. This progressive condition can ultimately lead to chronic kidney disease (CKD) and even kidney failure if left untreated.
As a Consultant Nephrologist and Transplant Physician in Pune, I often see patients who are unaware that their diabetes is silently affecting their kidney health. This blog aims to educate and empower you with the knowledge needed to protect your kidneys and take proactive steps for a healthier future.

What Is Diabetic Nephropathy?
Diabetic nephropathy is kidney damage caused by long-term, uncontrolled blood sugar levels. Over time, elevated glucose levels injure the small blood vessels (glomeruli) in the kidneys, making them less efficient at filtering waste from the blood. This condition develops slowly, usually over many years.
Why Is Diabetic Nephropathy Dangerous?
The kidneys perform a critical role in your body, removing toxins and excess fluid while maintaining a balance of electrolytes and hormones. When diabetes impairs kidney function, waste starts accumulating in the bloodstream, leading to complications such as:
High blood pressure
Fluid retention and swelling
Electrolyte imbalances
Anemia
Increased risk of heart disease
End-stage kidney failure, which requires dialysis or a transplant
Symptoms of Diabetic Nephropathy
In the early stages, diabetic nephropathy often shows no symptoms, which is why regular screening is essential. As the condition progresses, symptoms may include:
Swelling in feet, ankles, or hands
Fatigue and weakness
Increased urination, especially at night
Foamy or bubbly urine (a sign of protein leakage)
High blood pressure
Nausea or loss of appetite
How Is It Diagnosed?
Early detection is crucial. Diagnosis involves:
Urine test to detect albumin (a type of protein)
Blood test to measure kidney function (eGFR, creatinine)
Blood pressure monitoring
Imaging tests like ultrasound to assess kidney structure
Biopsy (in select cases) for confirmation
For people with diabetes, annual kidney screening is recommended.
Treatment Options
There is no complete cure for diabetic nephropathy, but early and effective management can significantly slow its progression. Treatment focuses on controlling the underlying causes and protecting kidney function.
1. Blood Sugar Control
Maintaining optimal blood glucose levels is the cornerstone of treatment. This may involve:
Medication adjustments
Insulin therapy
Diet and exercise plans
2. Blood Pressure Management
Keeping blood pressure below 130/80 mmHg is essential. ACE inhibitors or ARBs are often prescribed for kidney protection.
3. Kidney-Friendly Diet
A personalized renal diet may include:
Low sodium and potassium intake
Controlled protein consumption
Managing phosphorus levels
Fluid balance monitoring
4. Lifestyle Changes
Quit smoking
Maintain a healthy weight
Stay physically active
Avoid overuse of painkillers (NSAIDs), which can worsen kidney damage
5. Advanced Treatments
If kidney function declines significantly, patients may need:
Dialysis – to remove waste when kidneys fail
Kidney transplant – the most effective long-term solution for end-stage kidney disease
As a Transplant Specialist, I provide patients with comprehensive evaluation and support through every stage of the transplant process.
Can Diabetic Nephropathy Be Prevented?
Yes, in many cases, diabetic nephropathy can be prevented or delayed. Key preventive measures include:
Regular monitoring of kidney function
Tight control of blood sugar and blood pressure
Managing cholesterol and cardiovascular risk
Adhering to medications as prescribed
Routine consultation with a nephrologist if you have diabetes
When to See a Nephrologist?
If you have diabetes and experience swelling, fatigue, or abnormal urine findings, it’s time to consult a kidney specialist. Early referral can make a significant difference in outcomes.
Diabetic nephropathy is a serious but manageable condition. With timely diagnosis, appropriate treatment, and lifestyle modifications, you can protect your kidneys and live a full, healthy life—even with diabetes.
If you or a loved one is living with diabetes, don’t wait for symptoms to appear. Schedule a kidney health check-up with Dr. Bhupeshkumar Kaware, Consultant Nephrologist & Transplant Physician in Viman Nagar, Pune, for expert guidance and personalized care.
Read More:
Chronic Kidney Disease (CKD) | Dr. Bhupeshkumar Kaware